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Learn more about Gut Microbiome

Gut microbiome and Obesity

In 2013, Science Journal published a research paper that showed the correlation between obesity and the gut microbiome. Jeffrey Gordon and his team transplanted feces samples from different twin sisters (who each had different levels of obesity) into germ-free mice, respectively. Mice that received a fecal sample from an obese twin showed cases of obesity, and mice that received a fecal sample from a slim twin showed cases of leanness.

There was a difference in the level of obesity in mice when only the transplanted feces were changed from germ-free mice under the same conditions, suggesting that the gut microbiota may influence the induction of obesity. Imbalances in the gut microbiome can contribute to obesity by causing inflammation and changes in gut permeability and affecting energy metabolism. In addition, recent studies have mentioned specific microorganisms associated with obesity.

Reference :

  • Ridaura VK, Faith JJ, Rey FE, et al. Gut Microbiota from Twins Discordant for Obesity Modulate Metabolism in Mice. Science. September 2013

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Different functions

Beneficial gut bacterias help digest foods that are difficult to break down and synthesize essential nutrients such as vitamins B and K.

In particular, short-chain fatty acids (SCFA) produced by microorganisms in the large intestine are absorbed through the mucous membrane to strengthen the barrier and protect the intestine from harmful bacteria, creating an environment where beneficial bacteria can prevail.

The gut contains 70% of the immune cells that control the body's immunity. The gut microbiota can interact with immune cells to modulate the inflammatory response. If you create a balanced intestinal microbial ecosystem by increasing the ratio of beneficial bacteria, you can boost your defense against various bacterial and viral infections.

Reference :

  • Rowland I, Gibson G, Heinken A, et al. Gut microbiota functions:
    metabolism of nutrients and other food components. Eur J Nutr. April 2017

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Caring for the intestinal environment

An unhealthy diet and lifestyle can lead to an imbalance in your gut microbiome. If the number of harmful bacteria is abnormally higher than the number of beneficial bacteria, it may have a negative impact on the human body, causing various diseases. Harmful bacteria stimulate immune cells in the intestine, causing inflammation and producing toxins that weaken the intestinal mucosa.
Inflammation caused by gut microbiome imbalance may potentially lead to immune diseases, metabolic diseases, cerebrovascular and cardiovascular diseases.

Reference :

  • Makki K, Deehan EC, Walter J, Bäckhed F. The Impact of Dietary Fiber on Gut Microbiota in Host Health and Disease. Cell Host & Microbe. June 2018:

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Creating a Healthy Gut Environment

Improve Eating Habits

Excessive intake of high-fat meals containing animal fats, processed foods, and high fructose sugars can lead to an imbalance in the gut microbiome.
Create a healthy gut environment by increasing the diversity of intestinal microbes by eating low-fat meat, fish, poultry, vegetable fiber, and fermented foods.

Lifestyle Improvements

Exercising consistently increases the diversity of your gut microbiome and creates an environment in which beneficial bacteria thrive. Lack of sleep reduces the diversity of your gut microbiome.

Try to keep your intestinal environment healthy by improving your lifestyle, such as regular exercise and adequate sleep.

Monitoring Gut Microbiome Environment

Gut microbiome environment changes depending on one's diet and lifestyle. By identifying your microorganisms in your gut, it allows you to better understand what is required to create a healthier gut environment.

Check the changes in your gut microbiome through gut microbiome test every 3 months.

Take probiotics

Probiotics create a favorable environment for beneficial bacteria in the intestine and help with metabolism, immunity, and intestinal health.
Find the probiotics you need and take them regularly.

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